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|Pronunciation||/ æ m ˈ l oʊ d ɪ ˌ p iː n / |
|Trade names||Norvasc, others|
|License data||EU EMA: by INN, US DailyMed: Amlodipine, US FDA: Amlodipine|
|Pregnancy category||AU: C US: C (Risk not ruled out)|
|Routes of administration||By mouth|
|Drug class||Calcium channel blocker|
|ATC code||C08CA01 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Protein binding||93% |
|Metabolites||Various inactive pyrimidine metabolites|
|Onset of action||Highest availability 6–12 hours after oral dose|
|Elimination half-life||30–50 hours|
|Duration of action||At least 24 hours|
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Blockade of the renin-angiotensin system with ACE inhibitors, which inhibit the biosynthesis of angiotensin II from angiotensin I, is a mechanism of many drugs used to treat hypertension.to 1. 33, therefore Nephrologists have suggested renal biopsy to determine the proper function or rejection of the transplant kidney but there was no indication of rejection.
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In general, wait 7 to 14 days between titration steps.Based on the association between SBP at hypertensive visit and the required dose, the proposed starting dose for cats with a SBP 200 mmHg would be 1.
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With norvasc 5mg tablet once daily oral administration, antihypertensive effectiveness is maintained for at least 24 hours. Plasma concentrations correlate with effect in both young and elderly patients.Do not share this medication with others.
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