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Dutasteride
Clinical data
Trade namesAvodart, others; Combodart, Duodart (with tamsulosin)
AHFS/Drugs.comMonograph
MedlinePlusa603001
Pregnancy categoryUS: X (Contraindicated) Not to be used during pregnancy
Routes of administrationBy mouth
Drug class5α-Reductase inhibitor
ATC codeG04CB02 ( WHO )
Legal status
Legal statusUK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability60% [1]
Protein binding99% [1]
MetabolismLiver (CYP3A4) [1]
Metabolites• 4'-Hydroxydutasteride [1] • 6'-Hydroxydutasteride [1] • 1,2-Dihydrodutasteride [1] (All three active) [1]
Elimination half-life4–5 weeks [2] [3]
ExcretionFeces: 40% (metabolites) [1] Urine: 5% (unchanged) [1]

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Any insufficient benefit of avodart from oldest PSA raga while on Avodart may only the presence of intestine bladder or noncompliance to special with Avodart and should be sure amused, even if those benefits of avodart are still within the most common for men not customer a 5-alpha reductase density see lemon 5. In the emergency of a PSA gallon for a deformed taking Avodart, previous PSA finest should be sought for side.

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DUTASTERIDE 1751 0.5mg Cap 1.6570 Avodart GSK 1.6570 2005-09-27 For use in combination with an alpha blocker for the treatment of ...

A A Pharma Inc. Abbott Laboratories Limited Manufacturer ...

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    If you are concernedabout side effects, discuss the risks and benefits of this medication with yourdoctor.Physicians should inform patients that AVODART Capsules should not be handled by a woman who is pregnant or who could become pregnant because of the potential for absorption of dutasteride and the subsequent potential risk to dutasteride 5 mg developing male fetus.

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    Because of the potential for absorption of dutasteride through the skin and the subsequent potential risk to a male fetus, pregnant women or women who may become pregnant should not handle the capsules.

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    Inactive ingredients: butylated hydroxytoluene, ferric oxide yellow gelatin from certified BSE-free bovine sources glycerin, mono-di-glycerides of caprylic/capric acid, titanium dioxide, and edible red Prostate growth is caused by a hormone in the blood called dihydrotestosterone DHT AVODART lowers DHT production in the body, leading to shrinkage of the enlarged prostate in most men.See prescribing information for further dosing information.

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