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The absolute bioavailability of atorvastatin is approximately 12% and the systemic atorvastatin 10 price of HMG-CoA reductase inhibitory atorvastatin 10 price is approximately 30% The low systemic availability is attributed to presystemic clearance in gastrointestinal mucosa and/or hepatic first-pass metabolism Mean volume of distribution of atorvastatin is approximately 381 l.

Atorvastatin is 98% bound to plasma proteins.Appropriate studies have not been performed on the relationship of age to the effects of atorvastatin and ezetimibe combination in the pediatric population. Safety and efficacy have not been established.

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Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event see section 5.Atorvastatin is contraindicated during breast-feeding see section 4.

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In patients receiving amiodarone, diltiazem, or verapamil concomitantly with simvastatin, dosage of simvastatin should not exceed 10 mg daily.If the increase is only mild, you can continue to take the drug – soundofliberation.com/atorvastatin-medscape-2088426/lipitor-or-atorvastatin. Rarely, if the increase is severe, you may need to try a different statin.

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fatal CHD, nonfatal MI, and resuscitated cardiac arrest In addition, no difference in overall mortality was observed between atorvastatin- or simvastatin-treated patients, and the rates of death from cardiovascular or noncardiovascular causes were similar in both treatment groups.

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