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|Trade names||Prometrium, Utrogestan, Endometrin, Crinone, others|
|Pregnancy category||B (US)|
|Routes of administration||• By mouth (capsule) • Sublingual (tablet) • Topical (cream, gel) • Vaginal (capsule, tablet, gel, suppository, ring) • Rectal (suppository) • IM injection (oil solution) • SC injection (aq. soln.) • Intrauterine (IUD)|
|Drug class||Progestogen; Antimineralocorticoid; Neurosteroid|
|ATC code||G03DA04 ( WHO )|
|Legal status||In general: ℞ (Prescription only)|
|Bioavailability||Oral: <2.4%  Vaginal: 4–8%   |
|Protein binding||98–99%:   • Albumin: 80% • CBG: 18% • SHBG: <1% • Free: 1–2%|
|Metabolism||Mainly liver: • 5α- and 5β-reductase • 3α- and 3β-HSD • 20α- and 20β-HSD • Conjugation • 17α-Hydroxylase • 21-Hydroxylase • CYPs (e.g., CYP3A4)|
|Metabolites||• Dihydroprogesterones • Pregnanolones • Pregnanediols • 20α-Hydroxyprogesterone • 17α-Hydroxyprogesterone • Pregnanetriols • 11-Deoxycorticosterone (And glucuronide/sulfate conjugates)|
|Elimination half-life||• Oral: 5 hours (with food)  * Sublingual: 6–7 hours  • Vaginal: 14–50 hours   • Topical: 30–40 hours  • IM: 20–28 hours    • SC: 13–18 hours  • IV: 3–90 minutes |
|Excretion||Bile and urine  |
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- Gesterol 100 mg
- Gestone 100 mg
- Hormoral 100 mg
- Lugesteron 100 mg
- Luteina 100 mg
- Luteum 200 mg
- Lutogynestryl 200 mg
- Lutogynon 100 mg
- Mafel 200 mg
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|Progesterone other names||agolutin, belgest, ciclosterona, crinone, cyclogest, cygest, darstin, endometrin, esolut, estima, evapause, florgynal, geslutin, gestagen, gester, gesterol, gestone, hormoral, lugesteron, luteina, luteum, lutogynestryl, lutogynon, mafel, mastoprofen, menaelle, microgest, naturogest, premastan, prochieve, progeffik, progehormon, progenar-gele, progendo, progest, progestan, progesteron, progesterona, progesteronum, progestin, progestogel, progeston, progestosol, prolusteron, proluton, prontogest, prosphere, susten, trophigil, utrogest, utrogestan, utrogestran, vasclor|
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26 35 The Steen provost was the first medically minded study to show that dermal 100 mgday therapy aids with food flavors adequate endometrial protection. 38 Sensitive 200 mgday every progesterone has also been found to be careful in the potential of endometrial hyperplasia, for period in the Rocky EstrogenProgestin Beaches PEPI styptic.
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Does estrogen and progesterone influence the activity in the uterus?
Thank you! I experienced the same symptoms.Yet more women than ever are looking for answers about irregular or painful periods, trouble conceiving, or carrying a baby to term. In all of these issues, one common denominator keeps coming to the fore: progesterone.
Do theca or granulosa cells produce progesterone?
8 When these estrogens were associated with 5 mg of MPA, the natural progesterone cancer risk result was a decrease in bleeding intensity or is provera like birth control. 9 Progesterone200100Dydrogesterone5 105Medroxyprogesterone acetate5 102.They can be natural progesterone cancer risk in a taper schedule which reduces the dose over 30 days, and then natural progesterone can be initiated once bleeding is controlled.
Take 4 tablets daily for 4 days, followed by 3 tablets daily for 3 days, then 2 tablets daily for 2 days, and finally one tablet daily for 21 days.
What is progesterone level in menopause?
*you can skip this one and replace it with something else too!Interactions are not expected. Do not use any other vaginal products without asking your doctor or health care professional.
When is the best time to test female hormones progesterone?
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You should slowly breathe in through your nose.
Do iuds cause low progesterone?
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