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Its use has lessened due to safety concerns including potentially irreversible pigmentation a relatively high cost, and no evidence of any greater minocycline for skin than other acne treatments. A modified-release version of minocycline is being promoted as having fewer side-effects.Multum's drug information does not endorse drugs, diagnose patients or recommend therapy.

Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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Unauthorized use prohibited.The pharmacokinetics of minocycline in patients with renal impairment CLCR 80mL/min have not been fully characterized.

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